GETTING MY PALBOCICLIB TO WORK

mitotane will reduce the level or effect of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers decreases plasma focus of abemaciclib and its metabolites.Cell proliferation was assessed using a bromodeoxyuridine (BrdU) proliferation